Senior Scientist/Principal Scientist/Scientific Lead, Translational Sciences
Full Time
New York, NY
$75,000 - $110,000 a year
Posted
Job description
About Loxo@Lilly:
Loxo@Lilly aims to create medicines that make life better for all those affected by cancer around the world. Bringing together the focus and spirit of a biotech with the scale, resources, and heritage of Lilly, our team is focused on rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating oncology medicines that unequivocally show early signs of clinical activity and will matter to patients. We intend to curate a balanced pipeline of medicines, either internally or externally discovered, with the potential to treat cancer with dramatic effect. Loxo@Lilly was created in December 2019, combining the Lilly Oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. Loxo@Lilly is a global organization with team members in Louisville, Colorado; Indianapolis, Indiana; New York City, New York; San Diego, California; South San Francisco, California; Stamford, Connecticut; and Madrid, Spain.
The Senior/Principal Scientist/Scientific Lead, will be part of the Loxo@Lilly’s Translational Sciences group in New York. The Translational Sciences group is a central node in the Loxo@Lilly Oncology drug discovery organization with the mission to inform clinical biomarker strategy, enable clinical decision-making, address regulatory questions, and reverse-translate insights from the clinic to benefit next-generation drug development. Focus areas are coordinating and executing strategies for precision medicine including identifying and validating biomarkers, establishing combination strategies, and understanding drug resistance. The successful candidate must have strong organizational and managing skills and strong understanding of signal transduction pathways and be able to work with a positive, “can-do” attitude in a dynamic, fast-paced, team environment focused on high quality science to deliver innovative cancer drugs. This is a hands-on position for a scientist who enjoys working in the lab.
- Roles and Responsibilities of the Position:
- Identify, evaluate, and manage outsourced services
- Manage tumor samples, shipments, and external contracts
- Organize databases of studies in progress and planned
- Engage with business operations team to help executing contracts in a timely manner
- Ensure that external studies are run within expected timelines and anticipate and address potential issues
- Engage in cross-functional collaborations across the company and with external entities
- Design, coordinate and execute key studies in vitro and in vivo to evaluate compounds, identify combination partners and investigate drug resistance.
- Work closely with clinical and computational teams to develop and test hypotheses that could determine the clinical response and define the patient populations.
- Prepare reports and presentations for internal and external purposes including regulatory submissions.
- Participate and lead project-based and technical team meetings to identify and solve problems, guide work towards project goals, communicate on-going work and progress, and plan forward thinking strategies.
- Required Qualifications and Preferred Background:
- PhD in Molecular/Cellular Biology or Biochemistry, or related field with either:
- BS/MS in Molecular/Cellular Biology or Biochemistry with:
- Extensive experience in designing and running in vivo and in vitro studies
- Experience in managing contracts, samples, databases and domestic and international shipments
- Strong organizational abilities
- Experience in building up models (cell line, organoid or PDX) from patient samples and using them to test drug activities.
- Experience with general molecular biological techniques including q-PCR, ELISA, assays for protein-protein interactions and Western Blot etc.
- Strong background in experimental curve-fitting and statistics.
- Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels.
- Highly organized with excellent analytical, documentation and multi-tasking skills.
- Committed to staying current with the latest scientific breakthroughs in the targeted oncology field from target identification through human clinical trials.
- Enthusiastic, self-motivated and keen to improve processes and overcome inefficiencies
o 0-5 years hands-on molecular and cell biology experience in a post-doctoral/research/industry setting
o MS with 6+ years hands-on molecular and cell biology experience in a biotech/pharma setting or BS with 8+ years hands-on
molecular and cell biology experience a biotech/pharma setting.
Loxo@Lilly currently anticipates that the base salary for the Senior Scientist level position could range from between $75,000 to $110,000, and that the base salary for the Principal Scientist level position could range from $90,000 to $132,000, and that the base salary for the the Scientific Lead level position could range from $120,000 to $176,000, and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. This position will also be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Loxo provides a comprehensive benefit program to eligible employees, including vacation, medical, dental and vision benefits; participation in a 401(k) plan; life and accidental death and disability coverage; parental leave benefits and employee discounts for certain items. The compensation described above is subject to change and could be higher or lower than the range described.
Physical Demands/Travel:
The physical demands of this job are consistent with working in a laboratory/ bench environment. Some light lifting, and maneuvering may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position’s work environment is in a lab/bench environment.
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo@Lilly (Eli Lilly and Company) is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Loxo@Lilly (Eli Lilly and Company) is committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process for positions at Loxo, please email loxoaccommodation@loxooncology.com
for further assistance. Please note, this email address is intended for use to request an accommodation as a part of the application process. Any other correspondence will not receive a response.
caravetterealestate.com is the go-to platform for job seekers looking for the best job postings from around the web. With a focus on quality, the platform guarantees that all job postings are from reliable sources and are up-to-date. It also offers a variety of tools to help users find the perfect job for them, such as searching by location and filtering by industry. Furthermore, caravetterealestate.com provides helpful resources like resume tips and career advice to give job seekers an edge in their search. With its commitment to quality and user-friendliness, caravetterealestate.com is the ideal place to find your next job.