Job Summary:

The Scientist position will work with the Principal Investigator and will be responsible for developing new methodologies and methods of analysis in Dr. Doug McNeel's lab.

The goal of this research is to develop the immune based treatments for cancer using cancer vaccines through experimental methods, including development of new methods and new methods of analysis, in murine animal models, and analysis, in murine animal models, and analysis of specimens from human clinical trials.

The candidate will use prostate-tumor bearing mice to evaluate the ability of antigen-specific T cells, isolated and expanded from peripheral tissues, to be used to treat these tumors. The candidate will use T-cell receptor sequencing to characterize antigen-specific CD8 T cells, and use this information to quantify antigen-specific T cells in peripheral blood samples and tumor samples from experimental murine models and from human clinical trials. The candidate will evaluate chemically modified peptides for their ability to elicit peptide-specific immune responses using murine and human blood samples, and evaluate these modified peptides as anti-tumor vaccines using laboratory mice bearing prostate tumors. All of these studies will involve handling laboratory animals, and will require experience with flow cytometry, cell sorting, genetic sequencing, and immunological methods of analysis. Laboratory mouse methods (vaccination, intravenous delivery, necropsy), flow cytometry and methods of analysis, T cell receptor sequencing, ELISPOT, ELISA, and cell culture. The candidate will be working with collaborating laboratories and investigators for many of these studies, and will be required to analyze and prepare data for publications, public presentations, and preparation of grants.

SMPH is committed to being a diverse, equitable, inclusive and anti-racist workplace and is an Equal Employment Opportunity, Affirmative Action employer. Applications from Black, Indigenous and People of Color (BIPOC) individuals, LGBTQ+ and non-binary identities, women, persons with disabilities, military service members and veterans are strongly encouraged.

Responsibilities:

Identifies research problems, designs research methodologies, performs research, and helps to prepare the results for presentation to professional organizations or for scholarly publications to help advance research.

• 10% Assists with the identification of research problems and the development of research methodologies and procedures
• 70% Collects and analyzes research data, conducts experiments and interviews, and documents results according to established policies and procedures under general supervision and limited responsibility
• 5% Conducts literature reviews, prepares reports and materials, and disseminates information to appropriate entities
• 5% Attends and assists with the facilitation of scholarly events and presentations in support of continued professional development and the dissemination of research information
• 5% Writes or assists in developing grant applications and proposals to secure research funding
• 5% Serves as a main point of contact and liaison with internal and external stakeholders providing information and representing the interests of a specialized research area

Institutional Statement on Diversity:

Diversity is a source of strength, creativity, and innovation for UW-Madison. We value the contributions of each person and respect the profound ways their identity, culture, background, experience, status, abilities, and opinion enrich the university community. We commit ourselves to the pursuit of excellence in teaching, research, outreach, and diversity as inextricably linked goals.

The University of Wisconsin-Madison fulfills its public mission by creating a welcoming and inclusive community for people from every background - people who as students, faculty, and staff serve Wisconsin and the world.

For more information on diversity and inclusion on campus, please visit: Diversity and Inclusion

Education:

Required
PhD in Biological Science or other closely related field

Qualifications:

Prior experience with murine tumor models, immunological methods of analysis, flow cytometry, DNA sequencing methodologies required.

Work Type:

Full Time: 100%

It is anticipated this position requires work be performed in-person, onsite, at a designated campus work location.

Appointment Type, Duration:

Ongoing/Renewable

Salary:

$55,909 ANNUAL (12 months)
Fixed

Additional Information:

How to Apply:

Contact:

Devonne Tucker
dtucker@wisc.edu
608-263-9404
Relay Access (WTRS): 7-1-1. See RELAY_SERVICE for further information.

Official Title:

Scientist I(RE043)

Department(s):

A53-MEDICAL SCHOOL/CARBONE CANC CTR/CANC CTR

Employment Class:

Academic Staff-Renewable

Job Number:

274620-AS

The University of Wisconsin-Madison is an Equal Opportunity and Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to, including but not limited to, race, color, religion, sex, sexual orientation, gender identity, national origin, age, pregnancy, disability, or status as a protected veteran and other bases as defined by federal regulations and UW System policies. We promote excellence through diversity and encourage all qualified individuals to apply.

If you need to request an accommodation because of a disability, you can find information about how to make a request at the following website: https://employeedisabilities.wisc.edu/disability-accommodation-information-for-applicants/

Employment will require a criminal background check. It will also require you and your references to answer questions regarding sexual violence and sexual harassment.

The University of Wisconsin System will not reveal the identities of applicants who request confidentiality in writing, except that the identity of the successful candidate will be released. See Wis. Stat. sec. 19.36(7).

The Annual Security and Fire Safety Report contains current campus safety and disciplinary policies, crime statistics for the previous 3 calendar years, and on-campus student housing fire safety policies and fire statistics for the previous 3 calendar years. UW-Madison will provide a paper copy upon request; please contact the University of Wisconsin Police Department.