Scientist III, Assay Development and Screening

Full Time
Boston, MA 02210
Posted
Job description

Scismic is supporting the growth of a drug discovery biotech company based out of Boston, MA who is looking for a Scientist III to join their team!

Responsibilities:

  • Design appropriate in vitro biological assays and assist in defining screening funnels for small-molecule drug discovery projects within a variety of therapeutic areas.
  • Develop, optimize, and validate biochemical and cell-based assays in a timely and efficient manner. Prior experience with ELISA, TR-FRET, fluorescence-, and bioluminescence-based assay formats as well as analytical techniques such as HPLC will be a plus.
  • Contribute to compound management, automation, assay development, screening, and data management activities to identify small molecules meeting the Desired Chemical Characteristics (DCC) for each project.
  • Represent in vitro biology on project teams and work closely with colleagues across functional groups, including AI, Chemistry, and DMPK, to progress lead compounds.
  • Ensure experiments and results are documented appropriately in electronic laboratory notebooks and that processes are standardized and documented in SOPs that are rooted in industry standard practices.
  • Maintain clear and efficient communication.
  • Supervise and manage 1-3 Assay Biologists.

Qualifications:

  • A Ph.D. in Biology with a focus in Immunology, Neuroscience, Oncology, or a related field with post-doctoral plus at least 5 years of experience at a high-growth biotechnology or pharmaceutical company.
  • Experience with management of bench scientists.
  • Experience in assay development, high-throughput screening, and automation of biological assays.
  • Expertise in designing and executing screening test funnels to progress compounds from early drug discovery toward preclinical phases.
  • Independence and adeptness in ambiguous situations, flexibility, and comfort in making decisions using minimal available data.
  • A proven ability to work cross-functionally and adapt to changing priorities while managing multiple commitments with accuracy and efficiency to meet deadlines.

Compensation & Benefits:

  • Extremely generous equity package coupled with competitive salary
  • Excellent Healthcare benefits (employer covers 90% of insurance premiums)
  • Generous vacation and parental leave
  • Super cool team building activities
  • Flexible work schedule
  • Life Insurance (employer covers 100%)
  • 451D Gym Membership
  • Great colleagues

Job Type: Full-time

Schedule:

  • Monday to Friday

Work Location: In person

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